LY255283

Catalog No.S2959 Batch:S295901

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Technical Data

Formula

C19H28N4O3

Molecular Weight 360.45 CAS No. 117690-79-6
Solubility (25°C)* In vitro DMSO 72 mg/mL (199.75 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description LY255283 is an antagonist of leukotriene B4 (LTB4) receptor (BLT2) that displaces [3H]LTB4 from its binding site on lung membranes with pKi of 7.0.
Targets
BLT2 [1]
(Cell-free assay)
7.0(pKi)

Protocol (from reference)

Selleck's LY255283 has been cited by 1 publication

ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway [ J Transl Med, 2023, 21(1):923] PubMed: 38124204

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.