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Formula | C11H8Cl2N2O |
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Molecular Weight | 255.1 | CAS No. | 41931-13-9 | ||||||||
Solubility (25°C)* | In vitro | DMSO | 15 mg/mL (58.8 mM) | ||||||||
Ethanol | 6 mg/mL (23.52 mM) | ||||||||||
Water | Insoluble | ||||||||||
In vivo (Add solvents to the product individually and in order) |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
Description | LCS-1 is an inhibitor of superoxide dismutase 1(SOD1) with IC50 of 1.07 μM. | ||
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Targets |
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Flavonoids from Polypodium hastatum as neuroprotective agents attenuate cerebral ischemia/reperfusion injury in vitro and in vivo via activating Nrf2 [ Redox Rep, 2025, 30(1):2440204] | PubMed: 39702961 |
Mesenchymal stem cells enchanced by salidroside to inhibit ferroptosis and improve premature ovarian insufficiency via Keap1/Nrf2/GPX4 signaling [ Redox Rep, 2025, 30(1):2455914] | PubMed: 39874130 |
A novel molecular target, superoxide dismutase 1, in ALK inhibitor-resistant lung cancer cells, detected through proteomic analysis [ Exp Cell Res, 2024, 442(2):114266] | PubMed: 39313177 |
RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.