L-Histidine

Catalog No.S3989 Batch:S398901

Technical Data

Formula	C₆H₉N₃O₂
Molecular Weight	155.15	CAS No.	71-00-1
Solubility (25°C)*	In vitro	Water	31 mg/mL (199.8 mM)
		DMSO	Insoluble

* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description	L-Histidine (Glyoxaline-5-alanine) is an α-amino acid needed in humans for growth and tissue repair. It is used in the biosynthesis of proteins.
In vivo	L-histidine shows impairment on learning and memory processes. The administration of L-histidine (500 mg/kg i.p.) impairs performance in the shuttle-box, suggesting that an increase in cerebral histamine levels impairs the acquisition of avoidance response in rats^[1].

Protocol (from reference)

Animal Study:^{^[1]}	Animal Models male Swiss mice Dosages 500 mg/kg Administration i.p.

References

[1] Gianlorenço AC, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2011, 35(1):91-5.

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.