ICA-27243

Catalog No.E0105 Batch:E010501

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Technical Data

Formula

C12H7ClF2N2O

Molecular Weight 268.65 CAS No. 325457-89-4
Solubility (25°C)* In vitro DMSO 54 mg/mL (201.0 mM)
Ethanol 54 mg/mL (201.0 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description ICA-27243, a selective activator of the neuronal M current and KCNQ2/Q3 channels, induces a concentration-dependent increase in a 86Rb+ efflux from CHO cells expressing KCNQ2/Q3 channels with EC50 of 0.2 μM.
Targets
KCNQ2/Q3 channels [1]
(in a 86Rb+ efflux assay)
0.2 μM(EC50)

Protocol (from reference)

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.