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Technical Data
| Formula | C11H14O5 |
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| Molecular Weight | 226.23 | CAS No. | 6902-77-8 | |
| Solubility (25°C)* | In vitro | DMSO | 45 mg/mL (198.91 mM) | |
| Ethanol | 45 mg/mL (198.91 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Genipin((+)-Genipin) is an active aglycone derived from an iridoid glycoside called geniposide, which is found in the fruit of Gardenia jasminoides Ellis. |
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Protocol (from reference)
Customer Product Validation
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Data from [Data independently produced by , , Sci Rep, 2015, 5:17935]
Selleck's Genipin has been cited by 7 publications
| Genipin relieves diabetic retinopathy by down-regulation of advanced glycation end products via the mitochondrial metabolism related signaling pathway [ World J Diabetes, 2023, 10.4239/wjd.v14.i9.1349] | PubMed: 37771331 |
| The neuroprotective mechanism of lithium after ischaemic stroke [ Commun Biol, 2022, 5(1):105] | PubMed: 35115638 |
| Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice [ Front Pharmacol, 2022, 13:1038802] | PubMed: 36699054 |
| Signal transducer and transcriptional activation 1 protects against pressure overload-induced cardiac hypertrophy [ FASEB J, 2021, 35(1):e21240] | PubMed: 33377257 |
| Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor. [ J Cell Mol Med, 2020, 24(1):996-1009] | PubMed: 31701659 |
| Genipin inhibits the invasion and migration of colon cancer cells by the suppression of HIF-1α accumulation and VEGF expression [ Food Chem Toxicol, 2018, 116(Pt B):70-76] | PubMed: 29630948 |
| Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression. [Yu SX, et al. Sci Rep, 2015, 5:17935] | PubMed: 26659006 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.