Gemifloxacin mesylate

Catalog No.E0706 Batch:E070601

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Technical Data

Formula

C18H20FN5O4.CH4O3S

Molecular Weight 485.49 CAS No. 210353-53-0
Solubility (25°C)* In vitro DMSO 97 mg/mL (199.79 mM)
Water 97 mg/mL (199.79 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Gemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes.
In vivo

Gemifloxacin targets both DNA gyrase (preferred target) and topoisomerase IV (secondary target) – enzymes critical for DNA replication and organism survival – against clinical isolates of S. pneumoniae.[2]

Protocol (from reference)

Animal Study:

[2]

  • Animal Models

    strain BSP2443 of Streptococcus pneumoniae

  • Dosages

    --

  • Administration

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RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.