Fluphenazine dihydrochloride

Catalog No.S4569 Batch:S456901

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Technical Data

Formula

C22H26F3N3OS.2HCl

Molecular Weight 510.44 CAS No. 146-56-5
Solubility (25°C)* In vitro DMSO 100 mg/mL (195.9 mM)
Water 100 mg/mL (195.9 mM)
Ethanol 30 mg/mL (58.77 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Fluphenazine dihydrochloride (Prolixin) is a phenothiazine-class D1DR and D2DR inhibitor. It also inhibits Histamine H1 Receptor.

Protocol (from reference)

Animal Study:

[1]

  • Animal Models

    Male Wistar rats

  • Dosages

    1 mg/kg or 5 mg/kg

  • Administration

    i.p.

Selleck's Fluphenazine dihydrochloride has been cited by 3 publications

The Food and Drug Administration-approved antipsychotic drug trifluoperazine, a calmodulin antagonist, inhibits viral replication through PERK-eIF2α axis [ Front Microbiol, 2022, 13:979904] PubMed: 36386620
Reversal of Infected Host Gene Expression Identifies Repurposed Drug Candidates for COVID-19 [ bioRxiv, 2020, 2020/9/20.4.7.30734] PubMed: 32511305
CRISPR/Cas-Mediated Knockin in Human Pluripotent Stem Cells [Verma N, et al. Methods Mol Biol, 2017, 1513:119-140] PubMed: 27807834

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.