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Technical Data
| Formula | C17H18N2O2 |
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| Molecular Weight | 282.34 | CAS No. | 2719-05-3 | |
| Solubility (25°C)* | In vitro | DMSO | 56 mg/mL (198.34 mM) | |
| Ethanol | 1 mg/mL (3.54 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | FH1 is a small molecule, which promotes differentiation of iPS-derived hepatocytes. |
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| In vitro | In vitro, FH1(BRD-K4477) enhances hepatocyte functions, and promotes the maturation of well-differentiated cultures of iHeps, which potentially alleviates a major obstacle to the use of iPS cells as a renewable source of functional human hepatocytes. [1] |
Protocol (from reference)
Selleck's FH1 has been cited by 1 publication
| Highly efficient and expedited hepatic differentiation from human pluripotent stem cells by pure small-molecule cocktails. [ Stem Cell Res Ther, 2018, 9(1):58] | PubMed: 29523187 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.