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Technical Data
| CAS No. | 1256937-27-5 |
|---|---|
| Formulation | PBS Buffer, PH 7.4 |
| Isotype | Human IgG2 |
| Application | Evolocumab (anti-PCSK9) |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
| Purity | 99% |
| Protein concentration | 6.8mg/ml |
| Endotoxin Level | <1 EU/mg |
Biological Activity
| Description | Evolocumab (anti-PCSK9) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR. Evolocumab can be used for the research of hypercholesterolemia and atherosclerotic cardiovascular diseases. |
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Selleck's Evolocumab (anti-PCSK9) has been cited by 1 publication
| PCSK9 inhibitors ameliorate arterial stiffness in ACS patients: evidences from Mendelian randomization, a retrospective study and basic experiments [ Front Med (Lausanne), 2024, 11:1408760] | PubMed: 38860206 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.