DUBs-IN-2

Catalog No.E0389 Batch:E038901

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Technical Data

Formula

C15H9N5O
Molecular Weight 275.26 CAS No. 924296-19-5
Solubility (25°C)* In vitro  
 
 
In vivo (Add solvents to the product individually and in order)
Clear solution
5%DMSO Corn oil
0.09mg/ml Taking the 1 mL working solution as an example, add 50 μL of 1.7 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results. 
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Biological Activity

Description DUBs-IN-2 is a potent inhibitor of USP7 and USP8 deubiquitinating enzymes. 
Targets
USP8 [1]
(in the assay of inhibition of USP7 and USP8 deubiquitinating activity)		 USP7 [1]
(in the assay of inhibition of USP7 and USP8 deubiquitinating activity)
0.93 μM 7.2 μM

Protocol (from reference)

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.