DR2313

Catalog No.S6977 Batch:S697701

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Technical Data

Formula

C8H10N2OS

Molecular Weight 182.24 CAS No. 284028-90-6
Solubility (25°C)* In vitro Water 36 mg/mL (197.54 mM)
DMSO 18 mg/mL (98.77 mM)
Ethanol 5 mg/mL (27.43 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description DR2313 is a potent, selective, competitive and brain-penetrant inhibitor of poly(ADP-ribose) polymerase (PARP), with IC50s of 0.20 μM and 0.24 μM for PARP-1 and PARP-2, respectively. 
Targets
PARP-1 [1]
(in PARP inhibition assay)
PARP-2 [1]
(in PARP inhibition assay)
0.20 μM 0.24 μM

Protocol (from reference)

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.