Doxycycline monohydrate

Catalog No.S6068 Batch:S606801

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Technical Data

Formula

C22H26N2O9

Molecular Weight 462.45 CAS No. 17086-28-1
Solubility (25°C)* In vitro DMSO 47 mg/mL (101.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity.

Protocol (from reference)

Selleck's Doxycycline monohydrate has been cited by 13 publications

Pseudouridine synthase 1 regulates erythropoiesis via transfer RNAs pseudouridylation and cytoplasmic translation [ iScience, 2024, 27(3):109265] PubMed: 38450158
Methyltransferase like 7B is a potential therapeutic target for reversing EGFR-TKIs resistance in lung adenocarcinoma [ Mol Cancer, 2022, 21(1):43] PubMed: 35144642
Shh and Olig2 sequentially regulate oligodendrocyte differentiation from hiPSCs for the treatment of ischemic stroke [ Theranostics, 2022, 12(7):3131-3149] PubMed: 35547747
Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons [ Cell Rep, 2022, 39(1):110643] PubMed: 35385754
TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment [ EMBO Rep, 2022, e52984] PubMed: 35107856
BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer-promoter activity and maintains pluripotency [ Nucleic Acids Res, 2021, gkab034] PubMed: 33503260
Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer [ J Virol, 2021, 95(24):e0052921] PubMed: 34549974
Doxycycline sensitizes renal cell carcinoma to chemotherapy by preferentially inhibiting mitochondrial translation [ J Int Med Res, 2021, 49(10):3000605211044368] PubMed: 34644207
Differential Expression of MAGEA6 Toggles Autophagy to Promote Pancreatic Cancer Progression [ Elife, 2020, 9;9:e48963] PubMed: 32270762
Inhibition of BRAF Sensitizes Thyroid Carcinoma to Immunotherapy by Enhancing TsMHC-II-mediated Immune Recognition [ J Clin Endocrinol Metab, 2020, dgaa656] PubMed: 32936899

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.