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Technical Data
| Formula | C22H26N2O9 |
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| Molecular Weight | 462.45 | CAS No. | 17086-28-1 | |
| Solubility (25°C)* | In vitro | DMSO | 47 mg/mL (101.63 mM) | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. |
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Protocol (from reference)
Selleck's Doxycycline monohydrate has been cited by 13 publications
| Pseudouridine synthase 1 regulates erythropoiesis via transfer RNAs pseudouridylation and cytoplasmic translation [ iScience, 2024, 27(3):109265] | PubMed: 38450158 |
| Methyltransferase like 7B is a potential therapeutic target for reversing EGFR-TKIs resistance in lung adenocarcinoma [ Mol Cancer, 2022, 21(1):43] | PubMed: 35144642 |
| Shh and Olig2 sequentially regulate oligodendrocyte differentiation from hiPSCs for the treatment of ischemic stroke [ Theranostics, 2022, 12(7):3131-3149] | PubMed: 35547747 |
| Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons [ Cell Rep, 2022, 39(1):110643] | PubMed: 35385754 |
| TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment [ EMBO Rep, 2022, e52984] | PubMed: 35107856 |
| BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer-promoter activity and maintains pluripotency [ Nucleic Acids Res, 2021, gkab034] | PubMed: 33503260 |
| Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer [ J Virol, 2021, 95(24):e0052921] | PubMed: 34549974 |
| Doxycycline sensitizes renal cell carcinoma to chemotherapy by preferentially inhibiting mitochondrial translation [ J Int Med Res, 2021, 49(10):3000605211044368] | PubMed: 34644207 |
| Differential Expression of MAGEA6 Toggles Autophagy to Promote Pancreatic Cancer Progression [ Elife, 2020, 9;9:e48963] | PubMed: 32270762 |
| Inhibition of BRAF Sensitizes Thyroid Carcinoma to Immunotherapy by Enhancing TsMHC-II-mediated Immune Recognition [ J Clin Endocrinol Metab, 2020, dgaa656] | PubMed: 32936899 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.