Dibucaine HCl

Catalog No.S4038 Batch:S403801

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Technical Data

Formula

C20H29N3O2.HCl

Molecular Weight 379.92 CAS No. 61-12-1
Solubility (25°C)* In vitro DMSO 76 mg/mL (200.04 mM)
Water 76 mg/mL (200.04 mM)
Ethanol 76 mg/mL (200.04 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Dibucaine HCl (Cinchocaine) is a local anesthetics.
Targets
Sodium channel [2]
In vitro Dibucaine (Cinchocaine) HCl is one of the most potent and toxic of the long-acting local anesthetics. [1] Dibucaine (Cinchocaine) HCl blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. [2]

Protocol (from reference)

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.