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Technical Data
| Formula | C24H38N2.2Br |
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| Molecular Weight | 514.38 | CAS No. | 6159-05-3 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (194.4 mM) | |
| Water | 100 mg/mL (194.4 mM) | |||
| Ethanol | 100 mg/mL (194.4 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | DHBP (1,1'-diheptyl-4,4'-bipyridinium), a viologen for electrochromic memory display agent, inhibits the calcium release induced by 2 mM caffeine and 2 μg/ml polylysine with an IC50 value of 5 μg/ml and 4 μg/ml respectively. |
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| In vitro | DHBP is a putative inhibitor of ryanodine receptors (RyRs). It is an attractive water-soluble, cell-permeable and reversible experimental probe to understand the role of RyR's in cellular processes. DHBP (10-50 μM) significantly inhibits RyR-mediated Ca2+ release from sarcoplasmic reticulum (SR) in intact single fibers enzymatically isolated from murine flexor digitorum brevis (FDB) muscles. DHBP (10-50 μM) also inhibits SR Ca2+ release in ventricular epicardium of intact hearts[1]. |
Protocol (from reference)
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.