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Technical Data
| Formula | C43H79NO2
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| Molecular Weight | 642.09 | CAS No. | 1224606-06-7 | |
| Solubility (25°C)* | In vitro | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is a potent and ionizable cationic lipid. D-Lin-MC3-DMA is used for delivery of siRNA in vivo. | |||||
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| Density | 0.886 g/mL | |||||
Protocol (from reference)
Selleck's D-Lin-MC3-DMA (MC3) has been cited by 5 publications
| Engineering branched ionizable lipid for hepatic delivery of clustered regularly interspaced short palindromic repeat-Cas9 ribonucleoproteins [ iScience, 2024, 27(10):110928] | PubMed: 39381750 |
| Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy [ EMBO J, 2023, 42(2):e111673] | PubMed: 36514940 |
| Delivering mRNA to a human NK cell line, NK-92 cells, by lipid nanoparticles [ Int J Pharm, 2023, 636:122810] | PubMed: 36898618 |
| mRNA-Loaded Lipid Nanoparticles Targeting Dendritic Cells for Cancer Immunotherapy [ Pharmaceutics, 2022, 14(8)1572] | PubMed: 36015198 |
| PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling [ Sci Adv, 2022, 8(38):eabo0987] | PubMed: 36129984 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.