Chlorquinaldol

Catalog No.S4192 Batch:S419201

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Technical Data

Formula

C10H7Cl2NO

Molecular Weight 228.07 CAS No. 72-80-0
Solubility (25°C)* In vitro DMSO 46 mg/mL (201.69 mM)
Ethanol 6 mg/mL (26.3 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.
In vitro

Chlorquinaldol is a derivative of hydroxy-8-quinolein. For 0.1 to 0.2% (W/V) chlorquinaldol concentrations, a reduction of about 104 organisms is obtained after 60 minutes for N. gonorrhoeae and C. trachomatis. However, for technical problems, the concentrations tested are 10 to 100 times lower than the doses usually recommended for this antiseptic. [1] Chlorquinaldol displays enhanced bactericidal activity in duodeno-pancreatic secretions. [2]

Protocol (from reference)

Selleck's Chlorquinaldol has been cited by 3 publications

Insight into the Mode of Action of 8-Hydroxyquinoline-Based Blockers on the Histamine Receptor 2 [ Biosensors (Basel), 2023, 13(6)571] PubMed: 37366936
Insight into the Mode of Action of 8-Hydroxyquinoline-Based Blockers on the Histamine Receptor 2 [ Biosensors (Basel), 2023, 13(6)571] PubMed: 37366936
Discovery of 8-Hydroxyquinoline as a Histamine Receptor 2 Blocker Scaffold [ ACS Synth Biol, 2022, 11(8):2820-2828] PubMed: 35930594

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.