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Technical Data
| Formula | C58H73N13O21S2 |
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| Molecular Weight | 1352.40 | CAS No. | 17650-98-5 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (73.94 mM) | |
| Water | Insoluble | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Caerulein (Ceruletide, Cerulein, FI-6934), a cholecystokinin (CCK) receptor agonist, is a safe and effective cholecystokinetic agent and small bowel and exocrine pancreatic stimulant. Caerulein (FI-6934) can be used to induce animal models of acute pancreatitis. | |
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| In vivo | Low doses of the cholecystokinin agonists caerulein (0.00001 and 0.0001 mg/kg) elicits reduction of the nalaxone-induced jumping. The inhibition of jumping induced by caerulein is reduced with the selective cholecystokinin antagonists MK-329 and L-365,260. It is concluded that cholecystokinin mechanism(s) may be involved in its dependence, that the agonists may act on a presynaptic receptors.[2] |
Protocol (from reference)
References
RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.