Brincidofovir

Catalog No.E0938 Batch:E093801

Technical Data

Formula

C₂₇H₅₂N₃O₇P

Molecular Weight

561.69

CAS No.

444805-28-1

Solubility (25°C)*

In vitro

0.1mNAOH

10 mg/mL (17.8 mM)

DMSO

Insoluble

Water

Insoluble

In vivo (Add solvents to the product individually and in order)

Clear solution

5%0.1MNAOH 1 40%PEG300 2 5%Tween80 3 50%ddH2O

0.5mg/ml

Taking the 1 mL working solution as an example, add 50 μL of 50 mg/ml clarified 0.1MNAOH stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description	Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir with long-acting antiviral effect, shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections.

Protocol (from reference)

References

[1] Detweiler CJ, et al. J Pediatr Hematol Oncol. 2018 Aug;40(6):e364-e368.

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.