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Technical Data
| Formula | C9H9BrN2O3 |
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| Molecular Weight | 273.08 | CAS No. | 188011-69-0 | |
| Solubility (25°C)* | In vitro | DMSO | 54 mg/mL (197.74 mM) | |
| Water | Insoluble | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Bikinin is an ATP-competitive Arabidopsis GSK-3 inhibitor, and acts as a strong activator of brassinosteroid (BR) signaling. | |
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| Targets |
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| In vitro | Bikinin directly targets BIN2 of Arabidopsis GSK-3s and activates brassinosteroid-dependent gene expression. [1] Bikinin also inhibits RD26 expression, and inhibits the induction of GUS activity by 150 mM NaCl in the RD26pro:GUS line. [3] | |
| In vivo | Bikinin strongly inhibits abscisic acid signaling outputs, and inhibits T180 phosphorylation of SnRK2.3 and its kinase activity in vivo. [2] |
Protocol (from reference)
References
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Selleck's Bikinin has been cited by 3 publications
| Control of grain size in rice by TGW3 phosphorylation of OsIAA10 through potentiation of OsIAA10-OsARF4-mediated auxin signaling [ Cell Rep, 2023, 42(3):112187] | PubMed: 36871218 |
| The Histone Deacetylase 1/ GSK3/SHAGGY-Like Kinase 2/ BRASSINAZOLE RESISTANT 1 Module Controls Lateral Root Formation in Rice [ Plant Physiol, 2022, kiac015] | PubMed: 35078247 |
| WRKY53 Integrates Classic Brassinosteroid Signaling and the Mitogen-Activated Protein Kinase Pathway to Regulate Rice Architecture and Seed Size [ Plant Cell, 2021, koab137] | PubMed: 34003966 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.