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Technical Data
| CAS No. | 2173054-79-8 |
|---|---|
| Formulation | 100mMPro-Ac,20mMArg-Ac，pH5.0 |
| Isotype | Human IgG2SA |
| Source | CHO |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
| Purity | 99% |
| Protein concentration | 5.66mg/ml |
| Endotoxin Level | ＜1EU/mg |
Biological Activity
| Description | Astegolimab (Anti-IL-1RL1 / ST2 / IL-33R) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. It has the potential for chronic obstructive pulmonary disease (COPD), asthama treatment. MW :145.5 KD |
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Selleck's Astegolimab (Anti-IL-1RL1 / ST2 / IL-33R) has been cited by 1 publication
| Exploring the destructive synergy between IL-33 and Suilysin hemolysis on blood-brain barrier stability [ Microbiol Spectr, 2024, 12(8):e0061224] | PubMed: 38980021 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.