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Technical Data
| Formula | C8H13NO2.HBr |
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| Molecular Weight | 236.11 | CAS No. | 300-08-3 | |
| Solubility (25°C)* | In vitro | DMSO | 47 mg/mL (199.05 mM) | |
| Water | 47 mg/mL (199.05 mM) | |||
| Ethanol | 10 mg/mL (42.35 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Arecoline(NSC-31750) is a muscarinic acetylcholine receptor agonist. | |
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Protocol (from reference)
Customer Product Validation
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Data from [Data independently produced by , , Oncol Rep, 2015, 33(6):2753-60.]
Selleck's Arecoline HBr has been cited by 5 publications
| A Mechanistic Study of the Osteogenic Effect of Arecoline in an Osteoporosis Model: Inhibition of Iron Overload-Induced Osteogenesis by Promoting Heme Oxygenase-1 Expression [ Antioxidants (Basel), 2024, 13(4)430] | PubMed: 38671878 |
| Stromal thrombospondin 1 suppresses angiogenesis in oral submucous fibrosis [ Int J Oral Sci, 2024, 16(1):17] | PubMed: 38403794 |
| Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis. [ Oncogene, 2020, 39(11):2437-2449] | PubMed: 31974474 |
| Egr-1 mediates low-dose arecoline induced human oral mucosa fibroblast proliferation via transactivation of Wnt5a expression [ BMC Mol Cell Biol, 2020, 21(1):80] | PubMed: 33167868 |
| miR-203 inhibits arecoline-induced epithelial-mesenchymal transition by regulating secreted frizzled-related protein 4 and transmembrane-4 L six family member 1 in oral submucous fibrosis. [Zheng L, et al. Oncol Rep, 2015, 33(6):2753-60] | PubMed: 25872484 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.