Anti-mouse TIM-3 (CD366)-InVivo

Catalog No.A2131        Batch: A213102

       Clone No.B8.2C12

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Anti-mouse TIM-3 (CD366)-InVivo monoclonal antibody reacts with mouse TIM-3 (T cell immunoglobulin and mucin domain-3) also known as CD366. TIM-3 is specifically expressed at high levels on the surface of Th1 lymphocytes. This B8.2C12 antibody binds to the BALB/c allele of TIM-3 while reactivity to the C57Bl/6 allele. Inhibition of TIM-3 signaling in mice exacerbates experimental autoimmune encephalomyelitis and promotes IFNγ production and Th1 cell proliferation.

Technical Data

Formulation PBS, pH 7.0 Contains no stabilizers or preservatives
Clone B8.2C12
Isotype Rat IgG2a, κ
Application Anti-mouse TIM-3 (CD366)-InVivo
Storage
(From the date of receipt)
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility 5.03 mg/ml
Purity 99%
Protein concentration 5.03 mg/ml
Endotoxin Level <1EU/mg

Selleck's Anti-mouse TIM-3 (CD366)-InVivo has been cited by 1 publication

A novel vesicular stomatitis virus armed with IL-2 mimic for oncolytic therapy [ Virol Sin, 2024, S1995-820X(24)00146-9] PubMed: 39299564

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

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