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Anti-mouse TIM-3 (CD366)-InVivo
Catalog No.A2131 Batch: A213101
Clone No.B8.2C12
Anti-mouse TIM-3 (CD366)-InVivo monoclonal antibody reacts with mouse TIM-3 (T cell immunoglobulin and mucin domain-3) also known as CD366. TIM-3 is specifically expressed at high levels on the surface of Th1 lymphocytes. This B8.2C12 antibody binds to the BALB/c allele of TIM-3 while reactivity to the C57Bl/6 allele. Inhibition of TIM-3 signaling in mice exacerbates experimental autoimmune encephalomyelitis and promotes IFNγ production and Th1 cell proliferation.
Technical Data
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
|---|---|
| Clone | B8.2C12 |
| Isotype | Rat IgG2a, κ |
| Application | Anti-mouse TIM-3 (CD366)-InVivo |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| Sterility | 5.5mg/ml |
| Purity | 99% |
| Protein concentration | 5.5mg/ml |
| Endotoxin Level | ＜1EU/mg |
Selleck's Anti-mouse TIM-3 (CD366)-InVivo has been cited by 1 publication
| A novel vesicular stomatitis virus armed with IL-2 mimic for oncolytic therapy [ Virol Sin, 2024, S1995-820X(24)00146-9] | PubMed: 39299564 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.