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Anti-mouse CD8α-InVivo
Catalog No.A2102 Batch: A210216
Clone No.2.43
Anti-mouse CD8α (Clone:2.43)reacts with mouse CD8α. CD8 is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). It binds to class I MHC molecules displayed by antigen presenting cells (APC).
Technical Data
| Formulation | PBS buffer, pH 7.0 |
|---|---|
| Clone | 2.43 |
| Immunogen | Mouse CTL clone L3 |
| Isotype | Rat IgG2b, κ |
| Application | In vivo CD8+ T cell depletion,WB |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| Sterility | 7.99 mg/mL |
| Purity | 99% |
| Protein concentration | 7.99 mg/mL |
| Endotoxin Level | ＜1 EU/mg |
Customer Product Validation
Selleck's Anti-mouse CD8α-InVivo has been cited by 20 publications
| cGAS-activated endothelial cell-T cell cross-talk initiates tertiary lymphoid structure formation [ Sci Immunol, 2024, 9(98):eadk2612] | PubMed: 39093956 |
| Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity [ Cell Rep Med, 2024, 5(5):101533] | PubMed: 38744278 |
| Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade [ J Immunother Cancer, 2024, 12(9)e009327] | PubMed: 39244215 |
| Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer [ Cancer Lett, 2024, 589:216836.] | PubMed: 38556105 |
| Voluntary exercise sensitizes cancer immunotherapy via the collagen inhibition-orchestrated inflammatory tumor immune microenvironment [ Cell Rep, 2024, 43(9):114697] | PubMed: 39217611 |
| HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function [ Cell Oncol (Dordr), 2024, 10.1007/s13402-024-00959-1] | PubMed: 38809326 |
| Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells [ Nat Commun, 2023, 14(1):7709.] | PubMed: 38001101 |
| Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells [ Nat Commun, 2023, 14(1):7709] | PubMed: 38001101 |
| Enhanced Chemo-Immunotherapy Strategy Utilizing Injectable Thermosensitive Hydrogel for The Treatment of Diffuse Peritoneal Metastasis in Advanced Colorectal Cancer [ Adv Sci (Weinh), 2023, 10(35):e2303819] | PubMed: 37875399 |
| Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine [ Cell Rep Med, 2023, 4(10):101229] | PubMed: 37820722 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.