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Anti-mouse CD40L (CD154)-InVivo
Catalog No.A2112 Batch: A211201
Clone No.MR-1
The MR-1 monoclonal antibody reacts with mouse CD154 also known as CD40 ligand. The MR-1 monoclonal antibody has been reported to inhibit in vitro activation of B lymphocytes by blocking the binding of CD154 with CD40 on T helper cells as well as inhibit the formation of germinal centers and disrupt antigen-specific T cell responses. Additionally, the MR-1 antibody blocks interactions of T cells and antigen-presenting cells in vitro and blocks the development of experimental autoimmune disease in vivo.
Technical Data
| Formulation | PBS buffer, pH 7.0 |
|---|---|
| Clone | MR-1 |
| Immunogen | Activated mouse Th1 clone D1.6 |
| Isotype | Armenian Hamster IgG |
| Application | in vivo/vitro blocking of CD40/CD40L,WB |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| Sterility | 3.6mg/ml |
| Purity | 99% |
| Protein concentration | 3.6mg/ml |
| Endotoxin Level | ＜1EU/mg |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.