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Technical Data
| Formula | C20H22ClN3O |
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| Molecular Weight | 355.86 | CAS No. | 86-42-0 | |
| Solubility (25°C)* | In vitro | DMSO | 71 mg/mL (199.51 mM) | |
| Ethanol | 22 mg/mL (61.82 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria. |
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Protocol (from reference)
Selleck's Amodiaquine has been cited by 6 publications
| Amodiaquine ameliorates stress-induced premature cellular senescence via promoting SIRT1-mediated HR repair [ Cell Death Discov, 2024, 10(1):434] | PubMed: 39394181 |
| Drug Repositioning via Graph Neural Networks: Identifying Novel JAK2 Inhibitors from FDA-Approved Drugs through Molecular Docking and Biological Validation [ Molecules, 2024, 29(6)1363] | PubMed: 38542998 |
| A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics [ Nat Biomed Eng, 2021, 10.1038/s41551-021-00718-9] | PubMed: 33941899 |
| Human organ chip-enabled pipeline to rapidly repurpose therapeutics during viral pandemics [ bioRxiv, 2020, 10.1101/2020.04.13.039917] | PubMed: N/A |
| Reversal of Infected Host Gene Expression Identifies Repurposed Drug Candidates for COVID-19 [ bioRxiv, 2020, 2020/9/20.4.7.30734] | PubMed: 32511305 |
| Open drug discovery for the Zika virus. [ F1000Res, 2016, 5:150] | PubMed: 27134728 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.