Alosetron Hydrochloride

Catalog No.S4694 Batch:S469401

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Technical Data

Formula

C17H18N4O.HCl

Molecular Weight 330.81 CAS No. 122852-69-1
Solubility (25°C)* In vitro 4-Methylpyridine 7 mg/mL warmed with 50ºC water bath (21.16 mM)
Water 1 mg/mL (3.02 mM)
DMSO Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Alosetron Hydrochloride (GR 68755C, GR 68755X, Lotronex) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.
Targets
5-HT3 receptor [1]

Protocol (from reference)

Animal Study:[2]
  • Animal Models

    Sprague–Dawley rats

  • Dosages

    100 μg/kg

  • Administration

    i.v.

Selleck's Alosetron Hydrochloride has been cited by 2 publications

Pixantrone as a novel MCM2 inhibitor for ovarian cancer treatment [ Eur J Pharmacol, 2024, 979:176835] PubMed: 39032764
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways [Bellono NW Cell, 2017, 170(1):185-198] PubMed: 28648659

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.