Afm24 (Anti-EGFR & Fc-gamma-RIIIA)

Catalog No.A4048       

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Technical Data

CAS No. N/A
Source CHO
Storage
(From the date of receipt)
-80℃

Biological Activity

Description Afm24 is a human, tetravalent bispecific antibody targeting EGFR on tumor cells and the human low affinity IgG Fc region receptor IIIA (FCGR3A; CD16A) on innate immune cells. It enhances NK cell-mediated cytotoxicity and macrophage-driven phagocytosis, making it a promising immunotherapy with reduced EGFR-related toxicities for cancer treatment. M.W 196.34 kDa.

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

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