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Technical Data
| Formula | C14H18N6O.1/2 H2SO4 |
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| Molecular Weight | 335.35 | CAS No. | 188062-50-2 | |
| Solubility (25°C)* | In vitro | Water | 67 mg/mL (199.79 mM) | |
| DMSO | Insoluble | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Abacavir (1592U89) is a commonly used nucleoside analogue with potent antiviral activity against HIV-1. | |
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| Targets |
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| In vitro | Abacavir is an analog of guanosine (a purine). Its target is the viral reverse transcriptase enzyme. |
Protocol (from reference)
References
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Selleck's Abacavir sulfate has been cited by 6 publications
| Resurrection of endogenous retroviruses during aging reinforces senescence [ Cell, 2023, 186(2):287-304.e26] | PubMed: 36610399 |
| Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging [ Cell Rep, 2023, 42(6):112593] | PubMed: 37261950 |
| Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer [ Cancer Discov, 2022, candisc.1117.2021] | PubMed: 35320348 |
| Defining stable reference genes in HIV latency reversal experiments [ J Virol, 2021, JVI.02305-20] | PubMed: 33762410 |
| Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation [ Front Cardiovasc Med, 2021, 8:634774] | PubMed: 33898535 |
| Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice [ Invest Ophthalmol Vis Sci, 2015, 56(12):7122-9] | PubMed: 26529046 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.