Zalcitabine

Catalog No.S1719 Batch:S171904

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Technical Data

Formula

C9H13N3O3

Molecular Weight 211.22 CAS No. 7481-89-2
Solubility (25°C)* In vitro Water 42 mg/mL (198.84 mM)
DMSO 30 mg/mL (142.03 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Zalcitabine (NSC 606170, Ro 24-2027/000) is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).
Targets
HIV reverse transcriptase [1]

Protocol (from reference)

Selleck's Zalcitabine has been cited by 8 publications

Dexrazoxane inhibits the growth of esophageal squamous cell carcinoma by attenuating SDCBP/MDA-9/syntenin-mediated EGFR-PI3K-Akt pathway activation [ Sci Rep, 2024, 14(1):9167] PubMed: 38649770
Dexrazoxane inhibits the growth of esophageal squamous cell carcinoma by attenuating SDCBP/MDA-9/syntenin-mediated EGFR-PI3K-Akt pathway activation [ Sci Rep, 2024, 14(1):9167] PubMed: 38649770
Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer [ Cancer Discov, 2022, candisc.1117.2021] PubMed: 35320348
The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro [ Arch Toxicol, 2022, 1-20] PubMed: 35579693
Genotoxicity assessment of potentially mutagenic nucleoside analogues using ToxTracker® [ Toxicol Lett, 2022, 362:50-58] PubMed: 35569722
STING1 Promotes Ferroptosis Through MFN1/2-Dependent Mitochondrial Fusion [ Front Cell Dev Biol, 2021, 9:698679] PubMed: 34195205
Mitochondrial DNA Stress Triggers Autophagy-Dependent Ferroptotic Death [ Autophagy, 2020, 18;1-13] PubMed: 32186434
Time-Course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-Infected Human Gingival Fibroblasts. [ Front Cell Dev Biol, 2019, 7:204] PubMed: 31608279

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.