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Technical Data
| Formula | C15H12O7 |
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| Molecular Weight | 304.25 | CAS No. | 480-18-2 | |
| Solubility (25°C)* | In vitro | DMSO | 60 mg/mL (197.2 mM) | |
| Ethanol | 60 mg/mL (197.2 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on. | |
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| In vitro | Taxifolin is not mutagenic and low toxic compared to Qercetin. [1] It acts as a potential chemopreventive agent by regulating genes via an ARE-dependent mechanism. [2] Taxifolin has shown to inhibit the ovarian cancer cell growth in a dose-dependent manner. [3] |
Protocol (from reference)
References
Selleck's Taxifolin (Dihydroquercetin) has been cited by 3 publications
| Development of a genetic framework to improve the efficiency of bioactive delivery from blueberry [ Sci Rep, 2020, 10(1):17311] | PubMed: 33057109 |
| An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method [ J Med Virol, 2019, 91(8):1440-1447] | PubMed: 30900754 |
| Cell-based assay system for high-throughput screening of anti-photo-aging agents in fibroblast transfectants. [Lee S, et al. Cytotechnology, 2016, 68(4):1633-40] | PubMed: 26281901 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.