Rutin

Catalog No.S2350 Batch:S235002

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Technical Data

Formula

C27H30O16
Molecular Weight 610.52 CAS No. 153-18-4
Solubility (25°C)* In vitro DMSO 100 mg/mL (163.79 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Rutin (Rutoside), a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.
In vitro Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human. Rutin inhibits platelet aggregation as well as decreases capillary permeability, making the blood thinner and improving circulation. Recent studies show rutin could help prevent blood clots, so could be used to treat patients at risk of heart attacks and strokes. [1] [2]
In vivo LD50: Mice 650mg/kg (i.p.) [3]

Protocol (from reference)

Selleck's Rutin has been cited by 10 publications

Propafenone facilitates mitochondrial-associated ferroptosis and synergizes with immunotherapy in melanoma [ J Immunother Cancer, 2024, 12(11)e009805] PubMed: 39581704
Identification of the main flavonoids of Abelmoschus manihot (L.) medik and their metabolites in the treatment of diabetic nephropathy [ Front Pharmacol, 2023, 14:1290868] PubMed: 38313075
Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres [ Metabolites, 2022, 12(10)926] PubMed: 36295828
Rutin increases alpha-tubulin acetylation via histone deacetylase 6 inhibition [ Drug Dev Res, 2022, 10.1002/ddr.21927] PubMed: 35266183
Genetic and pharmacological PARP inhibition reduces axonal degeneration in C. elegans models of ALS [ Hum Mol Genet, 2022, ddac116] PubMed: 35594544
The protective effect of rutin against the cisplatin-induced cochlear damage in vitro [ Neurotoxicology, 2022, 90:102-111] PubMed: 35304134
Prevention of polycystic ovary syndrome and postmenopausal osteoporosis by inhibiting apoptosis with Shenling Baizhu powder compound [ PeerJ, 2022, 10:e13939] PubMed: 36325179
Role of Flavonoids in the Prevention of AhR-Dependent Resistance During Treatment with BRAF Inhibitors [ Int J Mol Sci, 2020, 21(14):5025] PubMed: 32708687
Rutin protects boar sperm from cryodamage via enhancing the antioxidative defense. [ Anim Sci J, 2020, 91(1):e13328] PubMed: 32219925
An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method [ J Med Virol, 2019, 91(8):1440-1447] PubMed: 30900754

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.