Miconazole

Catalog No.S2536 Batch:S253602

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Technical Data

Formula

C18H14Cl4N2O
Molecular Weight 416.13 CAS No. 22916-47-8
Solubility (25°C)* In vitro DMSO 83 mg/mL (199.45 mM)
Ethanol 83 mg/mL (199.45 mM)
Water Insoluble
In vivo (Add solvents to the product individually and in order)
Clear solution
5% DMSO 95% Corn oil
2.05mg/ml Taking the 1 mL working solution as an example, add 50 μL of 41 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results. 
Clear solution
5%DMSO 40%PEG300 5%Tween80 50%ddH2O
4.15mg/ml Taking the 1 mL working solution as an example, add 50 μL of 83 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results. 
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Miconazole (Monistat,R18134) is an imidazole antifungal agent.

Protocol (from reference)

Selleck's Miconazole has been cited by 6 publications

LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments [ Nat Commun, 2024, 15(1):3068] PubMed: 38594269
Terconazole, an Azole Antifungal Drug, Increases Cytotoxicity in Antimitotic Drug-Treated Resistant Cancer Cells with Substrate-Specific P-gp Inhibitory Activity [ Int J Mol Sci, 2022, 23(22)13809] PubMed: 36430288
Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations [ Chem Biol Interact, 2021, 343:109498] PubMed: 33961833
Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations [ Chem Biol Interact, 2021, 343:109498] PubMed: 33961833
Econazole Induces p53-Dependent Apoptosis and Decreases Metastasis Ability in Gastric Cancer Cells [ Biomol Ther (Seoul), 2020, 25] PubMed: 32209732
High-throughput liquid chromatography tandem mass spectrometry assay as initial testing procedure for analysis of total urinary fraction [ Drug Test Anal, 2020, 10.1002/dta.2917] PubMed: 32852861

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.