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Technical Data
| Formula | C32H44N2O8.HBr |
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| Molecular Weight | 665.61 | CAS No. | 97792-45-5 | |
| Solubility (25°C)* | In vitro | DMSO | 53 mg/mL (79.62 mM) | |
| Water | Insoluble | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects. |
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| In vitro | Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects. Its absorption percentage in rat stomachs after administration was 9.67%.The absorption percentages at duodenum,jejunum,ileum and colon were 19.61%,11.83%,12.95% and 9.51%, respectively.When the concentration was raised from 10 mg/L to 40 mg/L, the uptake of lappaconite hydrobromide was linearly increased,whereas the absorption rate constant kept at the same level. [1] |
| In vivo | LD50: Mice 10.5mg/kg (i.p.); Rats 9.9mg/kg (i.p.) [2] |
Protocol (from reference)
Selleck's Lappaconite HBr has been cited by 1 publication
| Yeast-Based Screen to Identify Natural Compounds with a Potential Therapeutic Effect in Hailey-Hailey Disease. [ Int J Mol Sci, 2018, 19(6)] | PubMed: 29925776 |
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.