Ferulic Acid

Catalog No.S2300 Batch:S230002

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Technical Data

Formula

C10H10O4

Molecular Weight 194.19 CAS No. 1135-24-6
Solubility (25°C)* In vitro DMSO 39 mg/mL (200.83 mM)
Ethanol 39 mg/mL (200.83 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.
Targets
FGFR1 [1]
(Cell-free assay)
FGFR2 [1]
(Cell-free assay)
3.78 μM 12.5 μM

Protocol (from reference)

Selleck's Ferulic Acid has been cited by 6 publications

Xuebijing improves intestinal microcirculation dysfunction in septic rats by regulating the VEGF-A/PI3K/Akt signaling pathway [ World J Emerg Med, 2024, 15(3):206-213] PubMed: 38855370
Strategies for lignin depolymerization and reconstruction towards functional polymers [ ROYAL SOCIETY OF CHEMISTRY, 2023, 7, 2953-2973] PubMed: none
Ferulic acid alleviates alveolar epithelial barrier dysfunction in sepsis-induced acute lung injury by activating the Nrf2/HO-1 pathway and inhibiting ferroptosis [ Pharm Biol, 2022, 60(1):2286-2294] PubMed: 36433644
An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method [ J Med Virol, 2019, 91(8):1440-1447] PubMed: 30900754
Ferulic acid increases intestinal Lactobacillus and improves cardiac function in TAC mice. [ Biomed Pharmacother, 2019, 120:109482] PubMed: 31568990
Resveratrol compounds inhibit human holocarboxylase synthetase and cause a lean phenotype in Drosophila melanogaster. [ J Nutr Biochem, 2015, 26(11):1379-84] PubMed: 26303405

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.