Dopamine HCl

Catalog No.S2529 Batch:S252903

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Technical Data

Formula

C8H11NO2.HCl
Molecular Weight 189.64 CAS No. 62-31-7
Solubility (25°C)* In vitro DMSO 38 mg/mL (200.37 mM)
Water 38 mg/mL (200.37 mM)
Ethanol Insoluble
In vivo (Add solvents to the product individually and in order)
Clear solution
5%DMSO 40%PEG300 5%Tween80 50%ddH2O
1.9mg/ml Taking the 1 mL working solution as an example, add 50 μL of 38 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results. 
Clear solution
5% DMSO 95% Corn oil
1.9mg/ml Taking the 1 mL working solution as an example, add 50 μL of 38 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results. 
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Dopamine HCl(ASL279, NSC 173182) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.
Targets
Dopamine receptor [1]

Protocol (from reference)

Selleck's Dopamine HCl has been cited by 6 publications

Generation of self-organized autonomic ganglion organoids from fibroblasts [ iScience, 2023, 26(3):106241] PubMed: 36922996
RECOVER identifies synergistic drug combinations in vitro through sequential model optimization [ Cell Rep Methods, 2023, 3(10):100599] PubMed: 37797618
The Food and Drug Administration-approved antipsychotic drug trifluoperazine, a calmodulin antagonist, inhibits viral replication through PERK-eIF2α axis [ Front Microbiol, 2022, 13:979904] PubMed: 36386620
Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes [ Cell, 2021, 184(4):943-956.e18] PubMed: 33571432
Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma [ Cancer Commun (Lond), 2020, 10.1002/cac2.12103] PubMed: 33017522
CD73-derived adenosine controls inflammation and neurodegeneration by modulating dopamine signalling. [ Brain, 2019, 142(3):700-718] PubMed: 30689733

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.