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Technical Data
| Formula | C24H40N8O4 |
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| Molecular Weight | 504.63 | CAS No. | 58-32-2 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (198.16 mM) | |
| Ethanol | 50 mg/mL (99.08 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Dipyridamole is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. | |
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Protocol (from reference)
Selleck's Dipyridamole has been cited by 7 publications
| Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity [ Haematologica, 2023, 108(9):2343-2357] | PubMed: 37021547 |
| Suppression of cell pyroptosis by omeprazole through PDE4-mediated autophagy in gastric epithelial cells. [ BIOCELL, 2023, 47(12): 2709-2719] | PubMed: none |
| Histone methyltransferase GLP epigenetically activates GPCPD1 to sustain cancer cell metastasis and invasion [ Genome Instability & Disease , 2023, 4:21–37 ] | PubMed: none |
| Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells [ Stem Cells, 2020, 38(8):1020-1033] | PubMed: 32346881 |
| Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells. [ Stem Cells, 2020, 28] | PubMed: 32346881 |
| Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes [Shen Q, et al. Am J Hum Genet, 2017, 100(1):5-20] | PubMed: 27939638 |
| PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma [ Oncogene, 2017, 36(23):3252-3262] | PubMed: 28092671 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.