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Technical Data
| Formula | C59H90O4 |
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| Molecular Weight | 863.34 | CAS No. | 303-98-0 | |
| Solubility (25°C)* | In vitro | 4-Methylpyridine | 23 mg/mL (26.64 mM) | |
| DMSO | Insoluble | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration.Solutions are unstable and should be fresh-prepared. |
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| In vitro | Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Coenzyme Q10 is found naturally in the energy-producing center of the cell known as the mitochondria. Coenzyme Q10 is found in the membranes of many organelles. Some other organelles that contain CoQ10 include endoplasmic reticulum, peroxisomes, lysosomes, and vesicles. Coenzyme Q10 also works as an antioxidant. [1] |
Protocol (from reference)
Customer Product Validation
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Data from [Data independently produced by , , Toxicology, 2016, 359-360:29-38]
Selleck's Coenzyme Q10 (CoQ10) has been cited by 6 publications
| Phospholipase PLA2G7 is complementary to GPX4 in mitigating punicic-acid-induced ferroptosis in prostate cancer cells [ iScience, 2024, 27(5):109774] | PubMed: 38711443 |
| Glycosaminoglycan-mediated lipoprotein uptake protects cancer cells from ferroptosis [ bioRxiv, 2024, 2024.05.13.593939] | PubMed: 38765991 |
| Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas [ Nat Commun, 2023, 14(1):3251] | PubMed: 37277330 |
| Pentafluorosulfanyl (SF5) as a Superior 19F Magnetic Resonance Reporter Group: Signal Detection and Biological Activity of Teriflunomide Derivatives [ ACS Sens, 2021, 10.1021/acssensors.1c01024] | PubMed: 34666481 |
| A novel investigation of statins myotoxic mechanism: effect of atorvastatin on respiratory muscles in hypoxic environment [ Toxicol Lett, 2019, 305:58-64] | PubMed: 30735765 |
| Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model. [El-Ganainy SO, et al. Toxicology, 2016, 359-360:29-38] | PubMed: 27345130 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.