Coenzyme Q10 (CoQ10)

Catalog No.S2398 Batch:S239805

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Technical Data

Formula

C59H90O4
Molecular Weight 863.34 CAS No. 303-98-0
Solubility (25°C)* In vitro 4-Methylpyridine 30 mg/mL (34.74 mM)
DMSO Insoluble
Water Insoluble
In vivo (Add solvents to the product individually and in order)
Clear solution
5%4-Methylpyridine 95%Corn oil
5.0mg/ml Taking the 1 mL working solution as an example, add 50 μL of 100 mg/ml clarified 4-Methylpyridine stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results. 
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration.Solutions are unstable and should be fresh-prepared.
In vitro Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Coenzyme Q10 is found naturally in the energy-producing center of the cell known as the mitochondria. Coenzyme Q10 is found in the membranes of many organelles. Some other organelles that contain CoQ10 include endoplasmic reticulum, peroxisomes, lysosomes, and vesicles. Coenzyme Q10 also works as an antioxidant. [1]

Protocol (from reference)

Customer Product Validation

Data from [Data independently produced by , , Toxicology, 2016, 359-360:29-38]

Selleck's Coenzyme Q10 (CoQ10) has been cited by 6 publications

Phospholipase PLA2G7 is complementary to GPX4 in mitigating punicic-acid-induced ferroptosis in prostate cancer cells [ iScience, 2024, 27(5):109774] PubMed: 38711443
Glycosaminoglycan-mediated lipoprotein uptake protects cancer cells from ferroptosis [ bioRxiv, 2024, 2024.05.13.593939] PubMed: 38765991
Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas [ Nat Commun, 2023, 14(1):3251] PubMed: 37277330
Pentafluorosulfanyl (SF5) as a Superior 19F Magnetic Resonance Reporter Group: Signal Detection and Biological Activity of Teriflunomide Derivatives [ ACS Sens, 2021, 10.1021/acssensors.1c01024] PubMed: 34666481
A novel investigation of statins myotoxic mechanism: effect of atorvastatin on respiratory muscles in hypoxic environment [ Toxicol Lett, 2019, 305:58-64] PubMed: 30735765
Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model. [El-Ganainy SO, et al. Toxicology, 2016, 359-360:29-38] PubMed: 27345130

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.