Carbidopa

Catalog No.S1891 Batch:S189102

Technical Data

Formula

C₁₀H₁₄N₂O₄

Molecular Weight

226.23

CAS No.

28860-95-9

Solubility (25°C)*

In vitro

DMSO

6.2 mg/mL (27.4 mM)

Water

Insoluble

Ethanol

Insoluble

In vivo (Add solvents to the product individually and in order)

Clear solution

4%DMSO 1 Corn oil

1.0mg/ml

Taking the 1 mL working solution as an example, add 40 μL of 25 mg/ml clear DMSO stock solution to 960 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description

Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.

Targets

aromatic-L-amino-acid decarboxylase ^[1]

29 μM

Protocol (from reference)

Selleck's Carbidopa has been cited by 3 publications

Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson's disease by regulating gut microbiota [ Signal Transduct Target Ther, 2021, 6(1):77]	PubMed: 33623004
Kynureninase contributes to the pathogenesis of psoriasis through pro-inflammatory effect [ J Cell Physiol, 2021, 10.1002/jcp.30587]	PubMed: 34553380
Dopamine D2 receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson's disease drugs, levodopa and piribedil, in neuronal cells [Lu J, et al. PLoS One, 2017, 12(3):e0173240]	PubMed: 28253352

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.