Bilobalide

Catalog No.S2276 Batch:S227602

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Technical Data

Formula

C15H18O8

Molecular Weight 326.30 CAS No. 33570-04-6
Solubility (25°C)* In vitro DMSO 65 mg/mL (199.2 mM)
Ethanol 65 mg/mL (199.2 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba.

Protocol (from reference)

Selleck's Bilobalide has been cited by 6 publications

Bilobalide ameliorates osteoporosis by influencing the SIRT3/NF-κB axis in osteoclasts and promoting M2 polarization in macrophages [ Int J Biol Macromol, 2024, 281(Pt 4):136504] PubMed: 39395513
Connexin43 is associated with the progression of clear cell renal carcinoma and is regulated by tangeretin to sygergize with tyrosine kinase inhibitors [ Transl Oncol, 2023, 35:101712] PubMed: 37354638
Synthetic, Mechanistic, and Biological Interrogation of Ginkgo biloba Chemical Space En Route to (-)-Bilobalide [ J Am Chem Soc, 2020, 142(43):18599-18618] PubMed: 32991152
Bilobalide Alleviated Dextran Sulfate Sodium-Induced Experimental Colitis by Inhibiting M1 Macrophage Polarization Through the NF-κB Signaling Pathway [ Front Pharmacol, 2020, 11:718] PubMed: 32670051
Intraperitoneal injection of ginkgolide B, a major active compound of Ginkgo biloba, dose-dependently increases the amount of wake and decreases non-rapid eye movement sleep in C57BL/6 mice. [ Neurosci Lett, 2020, 722:134832] PubMed: 32050100
Cell-based assay system for high-throughput screening of anti-photo-aging agents in fibroblast transfectants. [Lee S, et al. Cytotechnology, 2016, 68(4):1633-40] PubMed: 26281901

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.