β-Sitosterol

Catalog No.S2273 Batch:S227307

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Technical Data

Formula

C29H50O
Molecular Weight 414.71 CAS No. 83-46-5
Solubility (25°C)* In vitro Ethanol 5 mg/mL warmed with 50ºC water bath (12.05 mM)
DMSO Insoluble
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description β-Sitosterol (SKF 14463, 22,23-Dihydrostigmasterol) is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol.
In vitro

Β-Sitosterol is a plant sterol that interferes with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.

Protocol (from reference)

Cell Assay:

[1]
  • Cell lines

    KKU-M213 cells

  • Concentrations

    48.54 µM

  • Incubation Time

    72 h

  • Method

    Cells were treated with various concentrations of drug for 72 h.
Animal Study:

[2]
  • Animal Models

    Swiss Wistar rats

  • Dosages

    2.5 or 25 mg/kg

  • Administration

    p.o.

Selleck's β-Sitosterol has been cited by 1 publication

Investigation of the mechanism of Prunella vulgaris in treatment of papillary thyroid carcinoma based on network pharmacology integrated molecular docking and experimental verification [ Medicine (Baltimore), 2023, 102(17):e33360] PubMed: 37115092

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.