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Technical Data
| Formula | C10H15N3O5.HCl |
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| Molecular Weight | 293.7 | CAS No. | 14919-77-8 | |
| Solubility (25°C)* | In vitro | DMSO | 59 mg/mL (200.88 mM) | |
| Water | 59 mg/mL (200.88 mM) | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Benserazide HCl (Ro-4-4602) is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.Solutions are unstable and should be fresh-prepared. | ||
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Protocol (from reference)
Selleck's Benserazide HCl has been cited by 5 publications
| Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway [ Front Pharmacol, 2024, 15:1404532] | PubMed: 38828455 |
| Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum [ Elife, 2022, 11e72668] | PubMed: 35018884 |
| Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation [ Front Pharmacol, 2022, 13:903235] | PubMed: 35571135 |
| Kynureninase contributes to the pathogenesis of psoriasis through pro-inflammatory effect [ J Cell Physiol, 2021, 10.1002/jcp.30587] | PubMed: 34553380 |
| Glucose-sensing in AgRP neurons integrates homeostatic energy state with dopamine signalling in the striatum [ bioRxiv, 2021, 10.1101/2021.03.22.436393] | PubMed: None |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.