2,2,2-Tribromoethanol

Catalog No.S4508 Batch:S450802

Technical Data

Formula	C₂H₃Br₃O
Molecular Weight	282.76	CAS No.	75-80-9
Solubility (25°C)*	In vitro	DMSO	57 mg/mL (201.58 mM)
		Ethanol	57 mg/mL (201.58 mM)
		Water	29 mg/mL (102.56 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description	2,2,2-Tribromoethanol (TBE, Tribromoethanol) is an organic compound used to anesthetize animals.
In vivo	Tribromoethanol has been proposed as an acceptable anaesthetic in dogs, cats, mice, rats, and gerbils. It possesses a concentration dependent irritant effect. When used at low concentration, it displays good anesthetic effect. A high dose of tribromoethanol is not a suitable anesthetic for major surgery in all mouse strains because of the risk of pathologic changes in the abdominal organs, such as retention of the digestive tract, peritonitis, and fibrinoid adhesion^[1]^[2].

Description

2,2,2-Tribromoethanol (TBE, Tribromoethanol) is an organic compound used to anesthetize animals.

In vivo

Tribromoethanol has been proposed as an acceptable anaesthetic in dogs, cats, mice, rats, and gerbils. It possesses a concentration dependent irritant effect. When used at low concentration, it displays good anesthetic effect. A high dose of tribromoethanol is not a suitable anesthetic for major surgery in all mouse strains because of the risk of pathologic changes in the abdominal organs, such as retention of the digestive tract, peritonitis, and fibrinoid adhesion^[1]^[2].

Protocol (from reference)

Animal Study:^{^[2]}	Animal Models Male ICR, C57BL/6/Bkl, and BALB/c/Bkl mice Dosages 200 mg/kg Administration i.p.

References

Selleck's 2,2,2-Tribromoethanol has been cited by 3 publications

Targeting SPP1-orchestrated neutrophil extracellular traps-dominant pre-metastatic niche reduced HCC lung metastasis [ Exp Hematol Oncol, 2024, 13(1):111]	PubMed: 39529085
Traditional Chinese medicine Bu-Shen-Jian-Pi-Fang attenuates glycolysis and immune escape in clear cell renal cell carcinoma: results based on network pharmacology [ Biosci Rep, 2021, 41(6):BSR20204421]	PubMed: 34002799
Traditional Chinese medicine Bu-Shen-Jian-Pi-Fang attenuates glycolysis and immune escape in clear cell renal cell carcinoma: results based on network pharmacology [ Biosci Rep, 2021, 41(6)BSR20204421]	PubMed: 34002799

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.