1, 10-Phenanthroline monohydrate

Catalog No.S5543 Batch:S554301

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Technical Data

Formula

C12H8N2.H2O

Molecular Weight 198.22 CAS No. 5144-89-8
Solubility (25°C)* In vitro DMSO 39 mg/mL (196.75 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description 1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases.
Targets
metallopeptidase [1]

Protocol (from reference)

Selleck's 1, 10-Phenanthroline monohydrate has been cited by 2 publications

The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB [ Cell Rep, 2023, 42(6):112586] PubMed: 37267109
Administration of a microRNA-21 inhibitor improves the lupus-like phenotype in MRL/lpr mice by repressing Tfh cell-mediated autoimmune responses [ Int Immunopharmacol, 2022, 106:108578] PubMed: 35124415

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.