Sulfamethazine

Synonyms: Sulfadimidine,Sulfadimerazine

Sulfamethazine(Sulfadimidine,Sulfadimerazine) is a sulfonamide antibacterial.

Sulfamethazine Chemical Structure

Sulfamethazine Chemical Structure

CAS No. 57-68-1

Purity & Quality Control

Sulfamethazine Related Products

Biological Activity

Description Sulfamethazine(Sulfadimidine,Sulfadimerazine) is a sulfonamide antibacterial.
In vitro
In vitro

Sulfamethazine is an antibiotic used to treat bronchitis, prostatitis and urinary tract infections. Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase. In addition, sulfamethazine is a structural analog and competitive antagonist of para-aminobenzoic acid (PABA) and can inhibit normal bacterial utilization of PABA for the synthesis of folic acid, which is an important metabolite in DNA synthesis.

Chemical Information & Solubility

Molecular Weight 278.33 Formula

C12H14N4O2S

CAS No. 57-68-1 SDF Download Sulfamethazine SDF
Smiles CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 56 mg/mL ( (201.2 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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