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For research use only. Not for use in humans.
Simtuzumab (Anti-LOXL2)
Synonyms: AB 0024, GS 6624
Simtuzumab (Anti-LOXL2) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2) with potential antineoplastic activity. MW: 145.5 kD.
Quality Control
Batch:
A240801
Purity:
99%
Protein concentration: 11.22mg/ml
Endotoxin Level: ＜1EU/mg
99
Specificity
| Name | Citation | MAO-A | MAO-B | MAO | Others |
|---|---|---|---|---|---|
| Moclobemide (Ro 111163) | 4 | ||||
| Vafidemstat | 0 | LSD1/KDM1A | |||
| Norharmane | 0 | ||||
| MAO-B-IN-2 | 0 | BChE | |||
| Xanthoangelol | 1 | dopamine-beta-hydroxylase | |||
| 4-Hydroxyderricin | 0 | ||||
| Toloxatone (MD69276) | 0 | ||||
| TB5 | 0 | ||||
| Lazabemide | 0 | ||||
| Harmine | 5 | PPARγ | |||
| Isatin | 1 | ||||
| Sennoside A | 2 | ||||
| Paeonol | 2 | ||||
| Glycyrrhizin (NSC 167409) | 44 | HMGB1,11 beta-hydroxysteroid dehydrogenase | |||
| Harmane | 0 | ||||
| Iproniazid phosphate | 0 | ||||
| Myristicin | 0 | CYP1A2 | |||
| Hypericin | 1 | P450,Telomerase,Reverse transcriptase | |||
| Eprobemide | 0 | ||||
| Iproniazid | 0 |
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.
Mechanism of Action
| Description |
Simtuzumab (Anti-LOXL2) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2) with potential antineoplastic activity. MW: 145.5 kD.
|
|---|
Product Details
| CAS No. | 1318075-13-6 |
|---|---|
| Molecular Weight | 145.5 kDa |
| Isotype | Human IgG4SP |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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Products are for research use only. Not for human use. We do not sell to patients.
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