Home Microbiology Anti-infection chemical Ribitol For research use only.

Ribitol

Synonyms: Adonitol

Ribitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.

Ribitol Chemical Structure

Ribitol Chemical Structure

CAS No. 488-81-3

Purity & Quality Control

Ribitol Related Products

Biological Activity

Description Ribitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
In vitro
In vitro Ribitol is a crystalline pentose alcohol. [1] Ribitol is characterized from the plant Adonis vernalis. [2] Ribitol in 10% NFSM suspending medium exerts 1.45 to 2.18 times the protective effect exerted by glycerol at equal concentration. The cryoprotective action of Ribitol reaches its highest level at 0.75 M. For 11 of the 13 organisms tested including S. lactis T164, the degree of protection conferred by Ribitol is >80%. Ribitol has a strong protective effect on lactic acid bacteria during freeze-drying. [3]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03128489 Withdrawn
Diphtheria|Acellular Pertussis|Haemophilus Influenzae Type b|Tetanus|Poliomyelitis
GlaxoSmithKline
 December 1 2017 Phase 3
NCT02853929 Completed
Diphtheria|Hepatitis B|Acellular Pertussis|Haemophilus Influenzae Type b|Tetanus|Poliomyelitis|Diphtheria-Tetanus-aPertussis-Hepatitis B-Poliomyelitis-Haemophilus Influenzae Type b Vaccines
GlaxoSmithKline
 September 19 2016 Phase 4

Chemical Information & Solubility

Molecular Weight 152.15 Formula

C5H12O5
CAS No. 488-81-3 SDF Download Ribitol SDF
Smiles C(C(C(C(CO)O)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 31 mg/mL ( (203.74 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 31 mg/mL

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

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Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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