Home Neuronal Signaling AChR antagonist Propantheline bromide For research use only.

Propantheline bromide

Synonyms: Pro-Banthine, Neometantyl, Neopepulsan

Propantheline bromide (Pro-Banthine, Neometantyl, Neopepulsan) is a muscarinic antagonist used to treat gastrointestinal conditions associated with intestinal spasm and to decrease secretions during anesthesia.

Propantheline bromide Chemical Structure

Propantheline bromide Chemical Structure

CAS No. 50-34-0

Purity & Quality Control

Batch: S483401 DMSO]89 mg/mL]false]]]false]]]false Purity: 98%
98

Propantheline bromide Related Products

Signaling Pathway

AChR Signaling Pathways

AChR Signaling Pathway

Biological Activity

Description Propantheline bromide (Pro-Banthine, Neometantyl, Neopepulsan) is a muscarinic antagonist used to treat gastrointestinal conditions associated with intestinal spasm and to decrease secretions during anesthesia.
In Vivo
In vivo Propantheline bromide has poor oral activity[1].
Animal Research Animal Models Male Sprague-Dawley rats
Dosages 10, 30, 100, 300 mg/kg
Administration p.o.

Chemical Information & Solubility

Molecular Weight 448.39 Formula

C23H30NO3.Br
 
CAS No. 50-34-0 SDF --
Smiles CC(C)[N+](C)(CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13)C(C)C.[Br-]
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 89 mg/mL ( (198.48 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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