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Pancreatin

Name: Pancreatin
Brand: Selleck Chemicals
SKU: S4825
Rating: 5 (1 reviews)

Synonyms: Pancrelipase, Pancreatic enzymes

Catalog No.S4825 Purity:98%

Pancreatin (Pancrelipase, Pancreatic enzymes), are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems.(PROTEASE ACTIVITY ≥ 275 USP.u/mg；Amvlase activity ≥ 275 USP.u/mg；Lipase Activity ≥ 22 USP.u/mg)

Pancreatin Chemical Structure

CAS No. 8049-47-6

Purity & Quality Control

Batch: S482501 4-Methylpyridine]7 mg/mL]true]DMSO]0.01 mg/mL]false]Water]Insoluble]false Purity: 98%

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Biological Activity

Description	Pancreatin (Pancrelipase, Pancreatic enzymes), are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems.(PROTEASE ACTIVITY ≥ 275 USP.u/mg；Amvlase activity ≥ 275 USP.u/mg；Lipase Activity ≥ 22 USP.u/mg)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06023771	Recruiting	Acute Pancreatitis	Peking Union Medical College Hospital	October 2023	--
NCT05450627	Recruiting	Exocrine Pancreatic Insufficiency	Hospital Clinico Universitario de Santiago	June 1 2021	--
NCT05132309	Completed	Chronic Pancreatitis\|Pancreatic Exocrine Insufficiency	Federal Research and Clinical Center of Physical-Chemical Medicine\|Moscow State University of Medicine and Dentistry	November 1 2020	--
NCT04195347	Recruiting	Acute Pancreatitis	St. Jude Children''s Research Hospital\|CalciMedica Inc.	September 4 2020	Phase 1\|Phase 2
NCT04917172	Completed	Acute Pancreatitis\|Pancreatic Fistula\|Postoperative Complications	Azienda Ospedaliera Universitaria Integrata Verona	April 10 2019	--

Chemical Information & Solubility

Molecular Weight		Formula
CAS No.	8049-47-6	SDF	--
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

4-Methylpyridine : 7 mg/mL

DMSO : 0.01 mg/mL ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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